Handbook of the Biology of Aging
by Masoro, Edward J.; Austad, Steven N.; Masoro, Edward J.; Austad, Steven N.
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Summary
The Fifth Editionof the Handbook of the Biology of Agingcontinues the tradition of providing a comprehensive overview of some of the most important topics in biomedical gerontology. Beginning with an introduction to concepts and theories of aging, the book is then divided into three main sections covering cellular processes in organismic aging, systemic factors in organismic aging, and models of retarded aging. The book closes with a look at the future of biomedical research as it relates to aging, health, and longevity.
Table of Contents
Contributors | |
Foreword | |
Preface | |
About the Editors | |
Concepts and Theories of Aging | |
Oxidative Processes in Aging | |
Protein Structure and Turnover | |
Instability of the Nuclear Genome and the Role of DNA Repair | |
Alterations of the Mitochondrial Genome | |
Effect of Age on Gene Expression | |
Mitogen-Activated Protein Kinase Signaling Pathways and Aging | |
Cell Proliferation in Mammalian Aging | |
Apoptosis and Aging | |
Effects of Aging on the Sympathodrenal System | |
Endocrine and Neuroendocrine Regulatory Functions | |
Immune System Activity | |
The Genetics of Aging in Drosophila | |
Genetics of Increased Longevity and Retarded Aging in Mice | |
Dietary Restriction: An Experimental Approach to the Study of the Biology of Aging | |
Environment-Gene and Gene-Gene Interactions | |
Aging, Health, Longevity, and the Promise of Biomedical Research: The Perspective of a Gerontologist and Geriatrician | |
Author Index | |
Subject Index | |
Table of Contents provided by Blackwell. All Rights Reserved. |
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