Handbook of the Biology of Aging

by ; ; ;
Edition: 5th
Format: Paperback
Pub. Date: 2001-05-01
Publisher(s): Academic Pr
List Price: $74.95

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The Fifth Editionof the Handbook of the Biology of Agingcontinues the tradition of providing a comprehensive overview of some of the most important topics in biomedical gerontology. Beginning with an introduction to concepts and theories of aging, the book is then divided into three main sections covering cellular processes in organismic aging, systemic factors in organismic aging, and models of retarded aging. The book closes with a look at the future of biomedical research as it relates to aging, health, and longevity.

Table of Contents

About the Editors
Concepts and Theories of Aging
Oxidative Processes in Aging
Protein Structure and Turnover
Instability of the Nuclear Genome and the Role of DNA Repair
Alterations of the Mitochondrial Genome
Effect of Age on Gene Expression
Mitogen-Activated Protein Kinase Signaling Pathways and Aging
Cell Proliferation in Mammalian Aging
Apoptosis and Aging
Effects of Aging on the Sympathodrenal System
Endocrine and Neuroendocrine Regulatory Functions
Immune System Activity
The Genetics of Aging in Drosophila
Genetics of Increased Longevity and Retarded Aging in Mice
Dietary Restriction: An Experimental Approach to the Study of the Biology of Aging
Environment-Gene and Gene-Gene Interactions
Aging, Health, Longevity, and the Promise of Biomedical Research: The Perspective of a Gerontologist and Geriatrician
Author Index
Subject Index
Table of Contents provided by Blackwell. All Rights Reserved.

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