For courses in Organic Chemistry (2-Semester)

Paula Bruice’s presentation in Organic Chemistry, Eighth Edition provides mixed-science majors with the conceptual foundations, chemical logic, and problem-solving skills they need to reason their way to solutions for diverse problems in synthetic organic chemistry, biochemistry, and medicine. The Eighth Edition builds a strong framework for thinking about organic chemistry by unifying principles of reactivity that students will apply throughout the course, discouraging memorization. With more applications than any other textbook, Dr. Bruice consistently relates structure and reactivity to what occurs in our own cells and reinforces the fundamental reason for all chemical reactions—electrophiles react with nucleophiles. New streamlined coverage of substitution and elimination, updated problem-solving strategies, synthesis skill-building applications and tutorials guide students throughout fundamental and complex content in both the first and second semesters of the course.

Also Available with MasteringChemistry.

MasteringChemistry from Pearson is the leading online homework, tutorial, and assessment system, designed to improve results by engaging readers before, during, and after class with powerful content. Instructors ensure readers arrive ready to learn by assigning educationally effective content before class, and encourage critical thinking and retention with in-class resources such as Learning Catalytics^™. Readers can further master concepts after class through traditional and adaptive homework assignments that provide hints and answer-specific feedback. The Mastering gradebook records scores for all automatically graded assignments in one place, while diagnostic tools give instructors access to rich data to assess readers understanding and misconceptions.

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Note: You are purchasing a standalone product; MasteringChemistry does not come packaged with this content. Students, if interested in purchasing this title with MasteringChemistry, ask your instructor for the correct package ISBN and Course ID. Instructors, contact your Pearson representative for more information.

0134048148/9780134048147 Organic Chemistry Plus MasteringChemistry with eText -- Access Card Package, 8/e

Package consists of:

• 0134074661 / 9780134074665     MasteringChemistry with Pearson eText -- ValuePack Access Card -- for Organic Chemistry, 8/e
• 013404228X / 9780134042282     Organic Chemistry, 8/e

After graduating from the Girls’ Latin School in Boston, Paula Bruice earned an A.B. from Mount Holyoke College and a Ph.D. in chemistry from the University of Virginia. She then received an NIH postdoctoral fellowship for study in the Department of Biochemistry at the University of Virginia Medical School and held a postdoctoral appointment in the Department of Pharmacology at Yale Medical School. Paula has been a member of the faculty at the University of California, Santa Barbara since 1972, where she has received the Associated Students Teacher of the Year Award, the Academic Senate Distinguished Teaching Award, two Mortar Board Professor of the Year Awards, and the UCSB Alumni Association Teaching Award.

PART ONE: An Introduction to the Study of Organic Chemistry

1. Remembering General Chemistry: Electronic Structure and Bonding

2. Acids and Bases: Central to Understanding Organic Chemistry

TUTORIAL: Acids and Bases

3. An Introduction to Organic Compounds: Nomenclature, Physical Properties, and Structure

PART TWO: Electrophilic Addition Reactions, Stereochemistry, and Electron Delocalization

TUTORIAL: Using Molecular Models

4. Isomers: The Arrangement of Atoms in Space

TUTORIAL: Interconverting Structural Representations

5. Alkenes: Structure, Nomenclature, and an Introduction to Reactivity • Thermodynamics and Kinetics

TUTORIAL: Drawing Curved Arrows

6. The Reactions of Alkenes • The Stereochemistry of Addition Reactions

7. The Reactions of Alkynes • An Introduction to Multistep Synthesis

8. Delocalized Electrons: Their Effect on Stability, pKa, and the Products of a Reaction • Aromaticity and Electronic Effects: An Introduction the Reactions of Benzene

TUTORIAL: Drawing Resonance Contributors

PART THREE: Substitution and Elimination Reactions

9. Substitution and Elimination Reactions of Alkyl Halides

10. Reactions of Alcohols, Ethers, Epoxides, Amines, and Sulfur-Containing Compounds

11. Organometallic Compounds

12. Radicals

TUTORIAL: Drawing Curved Arrows in Radical Systems

PART FOUR: Identification of Organic Compounds

13. Mass Spectrometry; Infrared Spectroscopy; and UV/Vis Spectroscopy

14. NMR Spectroscopy

PART FIVE: Carbonyl Compounds

15. Reactions of Carboxylic Acids and Carboxylic Acid Derivatives

16. Reactions of Aldehydes and Ketones • More Reactions of Carboxylic Acid Derivatives

17. Reactions at the α-Carbon

TUTORIAL: Synthesis and Retrosynthetic Analysis

PART SIX: Aromatic Compounds

18. Reactions of Benzene And Substituted Benzenes

19. More About Amines • Reactions of Heterocyclic Compounds

PART SEVEN: Bioorganic Compounds

20. The Organic Chemistry Of Carbohydrates

21. Amino Acids, Peptides, and Proteins

22. Catalysis in Organic Reactions and in Enzymatic Reactions

23. The Organic Chemistry of the Coenzymes, Compounds Derived from Vitamins

24. The Organic Chemistry of the Metabolic Pathways

25.  The Organic Chemistry of Lipids

26. The Chemistry of the Nucleic Acids

PART EIGHT: Special Topics in Organic Chemistry

27. Synthetic Polymers

28. Pericyclic Reactions

Appendix I pK _a Values

Appendix II Kinetics

Appendix III Summary of Methods Used to Synthesize a Particular Functional Group

Appendix IV Summary of Methods Employed to Form Carbon-Carbon Bonds

Appendix V  Spectroscopy Tables

Appendix VI Physical Properties of Organic Compounds

Appendix VII Answers to Selected Problems