Oxford Textbook of Pediatric Pain

Our understanding of how pain in early life differs to that in maturity is continuing to increase and develop, using a combination of approaches from basic science, clinical science, and implementation science. The new edition of the Oxford Textbook of Pediatric Pain brings together an international team of experts to provide an authoritative and comprehensive textbook on all aspects of pain in infants, children, and youth.

Divided into nine sections, the textbook analyses pain as a multifactorial problem to give the reader a comprehensive understanding of this challenging subject. Evidence-based chapters look in depth at topics ranging from the long-term effects of pain in children, to complementary therapy in paediatric pain. The text addresses the knowledge-to-practice gap through individual and organizational implementation, and facilitation strategies. Case examples and perspective boxes are provided to aid learning and illustrate the application of knowledge.

Written by clinicians, educators, trainees, and researchers, hand selected by the Editors for their practical approach and expertise in specific subject areas, the new edition of the Oxford Textbook of Pediatric Pain is an essential reference text in the assessment and treatment of patients and families in the field of paediatric pain.

Bonnie J. Stevens, Professor, Lawrence S. Bloomberg Faculty of Nursing and Faculties of Medicine and Dentistry; and Associate Chief of Nursing Research, Senior Scientist Research Institute, The Hospital for Sick Children, Canada,Gareth Hathway, Associate Professor of Neuroscience, School of Life Sciences, The University of Nottingham, UK,William T. Zempsky, The Francine L. and Robert B. Goldfarb Endowed Chair for Pain and Palliative Medicine, Connecticut Children's Medical Center; and Professor of Pediatrics and Nursing, University of Connecticut, USA

Bonnie Stevens is a Professor at the Lawrence S. Bloomberg Faculty of Nursing and Faculties of Medicine and Dentistry at the University of Toronto. She is the Associate Chief of Nursing Research and a Senior Scientist in the Child Health Evaluative Sciences program at The Hospital for Sick Children. Dr Stevens is the Chair of the Certification Committee for ChildKind International. Dr Stevens focuses her research on the assessment and management of pain in hospitalized preterm newborn infants, and the effectiveness of knowledge translation (KT) strategies for changing clinical outcomes.

Gareth Hathway is a neuroscientist studying how pain in early life shapes experiences throughout the life course. He studied for a BSC (Hons) in Pharmacology at The University of Cardiff before studying for a PhD at The University of Cambridge. His post-doctoral work was carried out at UCL where he began to develop his interest in the maturation of endogenous pain control systems. Since 2009, he has led his own laboratory at The University of Nottingham continuing his work in early life pain physiology. As well as being an active researcher, he teaches on undergraduate programs in Neuroscience and Medicine and is the Course Director of Neuroscience BSc (Hons) and MSci (Hons) programs.

Dr Zempsky is Endowed Chair for Pain and Palliative Medicine at Connecticut Children's Medical Center, and a Professor of Pediatrics at the University of Connecticut School of Medicine. His division was designated a Center of Clinical Excellence by the American Pain Society in 2014, and is one of the first programs to receive the ChildKind certification focused on improving pain management for all children. Dr Zempsky was elected as Chair of the Pediatric Special Interest Group of the American Pain Society in 2015. He was appointed as the pediatric representative to the Physicians Medical Marijuana Board for the State of Connecticut in 2016. In 2017 he received the M1 mentoring grant from the University of Connecticut.

Section 1: Introduction
1. History of pain in children, Patrick J. McGrath and Bonnie J. Stevens
2. Prevalence of acute and chronic pain in children, William T. Zempsky
3. Long-term effects of early pain: animal models, Orla Moriarty and Suellen M. Walker
4. The long term effects of pain in children, Ruth E. Grunau, Jillian Vinall , and Cecil M.Y. Chau
5. Prevention of the development and maintenance of paediatric chronic pain and disability, Joel Katz, Brittany N. Rosenbloom, Gabrielle Pag?, and Anna Huguet
Section 2: Biological basis of paediatric pain
6. Nociceptive signalling in the periphery and spinal cord, Mark L. Baccei, Gareth Hathaway, and Charles M. Greenspon
7. Neuroimmune interactions and pain during postnatal development, Simon Beggs
8. Central nociceptive pathways and descending modulation, Maria Fitzgerald
9. Genetics and pain in childhood, Jeff S. Mogil
Section 3: Social and psychological basis of paediatric pain
10. Theoretical basis of pain, Liesbet Goubert, Rebecca Pillai Riddell, Laura Simons, and David Borsook
11. Culture, Margot Latimer
12. Families and pain, Christine T. Chambers, Kristen S. Higgins, Kathryn A. Birnie, and Katelynn E. Boerner
13. Pain, social relationships, and school
14. The effects of sex and gender on child and adolescent pain, Katelynn E. Boerner and Edmund Keogh
15. Pain and mental health, Maria Pavlova, Melanie Noel, Jillian Vinall , and Patritck J. McGrath
16. Sleep and pain in children and adolescents, Roc?o de la Vega, Joanne Dudeney, and Tonya M. Palermo
Section 4: Pain in specific populations and diseases
17. Pain in children with intellectual or developmental disabilities, Andrina MacDonald, Kristie Bennett, Jean Stansbury, Chantel C. Barney, John Belew, Scott Schwantes, Abraham J. Valkenburg, and Frank J. Symons
18. Paediatric cancer pain, Steve Wesiman
19. Pain management in major paediatric trauma and burns, Greta M. Palmer and Franz E. Babl
20. Needle procedures, Anna Taddio
21. Procedural sedation, Joseph P. Cravero and Daniel S. Tsze
22. Neuropathic pain in children, Madeleine Verriotis and Suellen M. Walker
23. Inflammatory arthritis and arthropathy, Laura Schanberg and Peter Chira
24. Chronic pain syndromes in childhood: one trunk, many branches, Neil L. Schechter
25. Non-inflammatory musculoskeletal pain, Jacqui Clinch
26. Pain in sickle cell disease, Carlton Dampier and Soumitri Sil
27. Pain and gastroenterological diseases, R.Mark Beattie and Akshay Batra
28. Postoperative pain management, Glyn Williams and Richard Howard
29. Pain in palliative care, Stefan Friedrichsdorf
30. Recurrent abdominal pain, Jennifer Verrill Schurman, Amanda Drews Deacy, and Craig A. Friesen
31. Chronic pelvic pain in children and adolescents, Susan L. Sager and Marc Laufer
32. Headaches, Andrew D. Hershey
33. Persisting pain in childhood medical illness, John Collins and Martha Mherekumombe
34. Common pain problems in the outpatient setting, F. Ralph Berberich and Neil L. Schechter
35. Effective management of children s pain and anxiety in the emergency department, Robert M. (Bo) Kennedy
Section 5: Measurement of pain
36. Neonatal and infant pain assessment, Mariana Bueno , Mats Eriksson, and Bonnie J. Stevens
37. Self-report: the primary source in assessment after infancy, Carl L. von Baeyer and Mark Connelly
38. Behavioural measures of pain, Jill M. Chorney and C. Meghan McMurtry
39. Physiological measurement, Tim Oberlander, Susanne Brummelte, Naama Rotem-Kohavi, and Kenneth D. Craig
40. Brain responses Neurophysiological evaluation of nociceptive responses in neonates, Rebeccah Slater and Caroline Hartley
41. Measurement of health-related quality of life and physical function, Tonya M. Palermo, See Wan Tham , Anna C. Wilson, and Lexa K. Murphy
Section 6: Pharmacological interventions
42. Principles of pain pharmacology in paediatrics, Karel Allegaert, Sinno H. P. Simons, and Dick Tibboel
43. The non-steroidal anti-inflammatory drugs and acetaminophen, Brian Anderson
44. Developmental pharmacology of opioids, Gareth Hathway
45. Opioids in clinical practice, Howard Meng, Scott A. Strassels, and Fiona Campbell
46. Interventional pain management techniques for chronic pain, Navil F. Sethna, Walid Alrayashi, Pradeep Dinakar, and Karen R. Boretsky
47. Topical anaesthetics and analgesics, William T. Zempsky
48. Drugs for neuropathic pain, Sachin Rastogi and Fional Campbell
49. Sucrose and sweet taste, Denise Harrison, Janet Yamada, and Mariana Bueno
50. Cannabis, Mark Ware, Pablo Ingelmo, and Rebecca Pitt
Section 7: Psychosocial interventions
51. Psychosocial interventions, Kristen Uhl, Laura A. Wright, Rachael M. Coakley , and Deirdre E. Logan
52. Procedural pain distraction, Lindsey L. Cohen, Laura A. Wright, Sarah R. Martin, Sharon Shih, and Matthew Donati
Section 8: Physical interventions
53. Therapeutic management of pain, Liisa Holsti, Susan Tupper, Joyce M. Engel, and Mary Swiggum
54. Mother care for procedural pain in infants, Marsha Campbell-Yeo, Celeste Johnston, Britney Benoit, and Brianna Richardson
Section 9: Special topics
55. Complementary drugs herbs, vitamins, and dietary supplements for pain and symptom management, Joy A. Weydert
56. Complementary therapy in paediatric pain, Lonny K. Zeltzer and Sarah R. Martin
57. Theory-informed approaches to translating pain evidence into practice, Janet Yamada, Alison M. Hutchinson, and Shelly-Anne Li
58. Knowledge translation strategies for mobilizing Individuals, Christine T. Chambers, Melanie Barwick, and Perri Tutelman
59. Knowledge translations strategies for mobilizing organization, Stefan Friedrichsdorf, Alison Twycross, and Bonnie J. Stevens
60. New information and communication technologies for pain, Lindsay A. Jibb and Jennifer N. Stinson
61. The ethics of pain control in infants and children, Kenneth D. Craig and Adam Shriver
62. Sociodemographic disparities in paediatric pain management: relationships and predictors, Anna Huguet and Miriam O. Ezenwa